Current solutions for the monitoring of pulmonary artery pressure (PAP) in patients suffering from pulmonary hypertension are limited to invasive means. Non-invasive alternatives, such as Doppler echocardiography, are incompatible with continuous monitoring due to their dependency on qualified personnel to perform the measurements. In the present study, a novel non-invasive and unsupervised approach based on the use of electrical impedance tomography (EIT) is presented. The approach was evaluated in three healthy subjects undergoing hypoxia-induced variations in PAP. A timing parameter - physiologically linked to the PAP via the so-called pulse wave velocity principle - was automatically extracted from the EIT data. Reference systolic PAP estimates were obtained by echocardiography. Strong correlation scores (r e [0.844, 0.990]) were found between the EIT-derived parameter and the reference PAP, thereby suggesting the validity of the proposed approach. If confirmed in larger datasets, these findings could open the way for a new branch of fully non-invasive hemodynamic monitors for patients with pulmonary hypertension.

Additional Metadata
Persistent URL dx.doi.org/10.1109/EMBC.2016.7591662
Conference 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Citation
Proenca, M., Braun, F., Muntane, E., Sola, J., Adler, A, Lemay, M., … Rimoldi, S.F. (2016). Non-invasive monitoring of pulmonary artery pressure at the bedside. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 4236–4239). doi:10.1109/EMBC.2016.7591662