Methylmercuration of cytidine‐3′‐monophosphate is shown to occur at the N‐3 site, resulting in a substantial upfield shift in the 15N resonance of this nitrogen. For guanosine‐5′‐monophosphate the 15N NMR data show N‐1 to be the site of complexation of CH3Hg+ at pH 8. The large downfield shift observed for N‐1 as a result of this binding is explained in terms of a concomitant deprotonation phenomenon. Changes in 13C NMR chemical shifts on methylmercuration are less pronounced, but consistent with these binding sites. Copyright

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Persistent URL dx.doi.org/10.1002/mrc.1260240604
Journal Magnetic Resonance in Chemistry
Citation
Buchanan, G.W, & Bell, M.‐J. (1986). Mercuration effects on nucleoside chemical shifts: 15N and 13C NMR studies of methylmercury(II) ion addition to cytidine‐3′‐monophosphate and guanosine‐5′‐monophosphate. Magnetic Resonance in Chemistry, 24(6), 493–497. doi:10.1002/mrc.1260240604