Objective: To examine whether, like pure obsessive-compulsive disorder, obsessive-compulsive spectrum disorders are treatable with a selective serotonin reuptake inhibitor (SSRI). Method: Case histories of patients prescribed paroxetine for compulsive collecting skin-picking, and trichotillomania were reviewed. Results: All patients were successfully treated with paroxetine. Conclusions: Obsessive-compulsive spectrum disorders may share a serotonin-related dysfunction, and SSRIs may prove effective in their treatment.

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Canadian Journal of Psychiatry
Department of Psychology

Ravindran, A.V. (Arun V.), Lapierre, Y.D. (Yvon D.), & Anisman, H. (1999). Obsessive-compulsive spectrum disorders: Effective treatment with paroxetine. Canadian Journal of Psychiatry, 44(8), 805–807.