Summary Simulated sequence alignments are frequently used to test bioinformatics tools, but current sequence simulators are limited to defined state spaces. Here, we present the COMPletely Arbitrary Sequence Simulator (COMPASS), which is able to simulate the evolution of absolutely any discrete state space along a tree, for any form of time-reversible model.

Additional Metadata
Persistent URL dx.doi.org/10.1093/bioinformatics/btx347
Journal Bioinformatics
Citation
Low, A. (Andrew), Rodrigue, N, & Wong, A. (2017). COMPASS: The COMPletely Arbitrary Sequence Simulator. Bioinformatics, 33(19), 3101–3103. doi:10.1093/bioinformatics/btx347