2002-06-04
A comparison of oleamide in the brains of hibernating and non-hibernating Richardson's ground squirrel (Spermophilus richardsonii) and its inability to bind to brain fatty acid binding protein
Publication
Publication
Journal of Thermal Biology , Volume 27 - Issue 4 p. 309- 315
Hibernation has been suggested to cause sleep debt, and since oleamide is elevated in the central nervous system of sleep-deprived mammals we hypothesized that brains from hibernating mammals would contain more oleamide than those that were not hibernating. Oleamide was 2.6-fold greater in brains of hibernating Richardson's ground squirrel (Spermophilus richardsonii) than in euthermic brains. Additionally, brain fatty acid-binding protein did not bind oleamide and does not represent a solubilized pool of oleamide.
Additional Metadata | |
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Brain fatty acid-binding protein, Hibernation, Oleamide, Richardson's ground squirrel, Sleep deprivation | |
dx.doi.org/10.1016/S0306-4565(01)00093-6 | |
Journal of Thermal Biology | |
Organisation | Department of Biology |
Stewart, J.M., Boudreau, N.M., Blakely, J.A., & Storey, K. (2002). A comparison of oleamide in the brains of hibernating and non-hibernating Richardson's ground squirrel (Spermophilus richardsonii) and its inability to bind to brain fatty acid binding protein. Journal of Thermal Biology, 27(4), 309–315. doi:10.1016/S0306-4565(01)00093-6
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