The purpose of this report is to provide a review of the effects of low-power photo-induced therapy using lasers of different device parameters such as intensity, wavelength, lasing mechanism (i.e., pulsed or continuous) on the production of Adenosine triphosphate (ATP) in mammalian cells. This is a very important research topic as it is suggested in literature that there might be a relationship between the ATP levels and specific diseases. It has been shown that the ATP production was enhanced at wavelengths ranging between 600 nm and 1000 nm (also known as the optical window), in particular at 600nm, 632.8nm, 635nm, 650nm, and 904nm. However, certain experiments showed that the effectiveness of the photo-induced therapy was also dependent on the dosage and the duration of the supplied light. We present the research conclusions drawn from the experiments reported within the last decade, and provide a list of potential medical treatment(s) for patients using visible and near infrared (NIR) light.

Additional Metadata
Keywords ATP, Lasers, Low-level laser therapy (LLLT), NIR, Photo-induced therapy, Wavelength
Persistent URL dx.doi.org/10.1117/12.2001464
Conference Photonics North 2012
Citation
Abdalla, M. (M.), Nagy, A. (A.), Ye, W.N, & Mussivand, T. (T.). (2012). Overview of photo-induced therapy for ATP production. In Proceedings of SPIE - The International Society for Optical Engineering. doi:10.1117/12.2001464