Label-free Detection of Dopamine Using Aptamer Enhanced Organic-Electrolyte Gated FET Sensor
In this work we implemented low cost, organic transistors for biosensory application. The sensor is fabricated primarily at low temperatures and atmospheric pressures using additive manufacturing steps and implemented as Aptamer enhanced Organic Electrolyte Gated Field Effect Transistors (OEGFETs), for detection of vital small molecules in fluid samples. To characterize the OEGFET performance, we collected I-V transfer curves of the transistor with different electrolytic solutions, with and without immobilized aptamers. The motivation behind this work is the need for accurate, non-invasive biofluid testing devices. Label-free sensing such as that offered by our OEGFET simplifies the testing procedure and creates a device framework that can be applied to rapidly and accurately detect a variety of biomolecules.
|1st IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS 2019|
|Organisation||Ottawa-Carleton Chemistry Institute|
Massey, R. (R.), Morin, E. (E.), DeRosa, M.C, & Prakash, R. (R.). (2019). Label-free Detection of Dopamine Using Aptamer Enhanced Organic-Electrolyte Gated FET Sensor. In FLEPS 2019 - IEEE International Conference on Flexible and Printable Sensors and Systems, Proceedings. doi:10.1109/FLEPS.2019.8792324