A conference named Frontiers of Chemical Sciences III: Research & Education in the Middle East was held at Istanbul, Turkey. The meeting was third in the series of conferences with an aim of engendering goodwill and collaboration among Middle Eastern scientists that may change their job back to politicians. The conference was aimed to meet on middle ground to generally discuss regional, research, and environmental issues. The main topics that were discussed include water quality and quantity, water drop, contamination of water resources with higher levels of lead, nitrate, and chloride. Nitrate contamination from agricultural runoff was linked with the incidences of renal failure and infants who suffer from methemoglobinemia, a condition that leads to blue-gray skin, coma, and death. A wide variety of regional science was discussed that include biomineralization and nanofabrication to new sources of alternative energy.