Some of the significant advantages of unstructured proteins and their application in several fields are discussed. Many of the unstructured proteins are being applied in significant processes, ranging cell division to gene transcription. These unstructured proteins are also involved in disease processes, including cancer, Alzheimer's, and Parkinson diseases. Researchers suggest that the intrinsic character of disorder provides plasticity and flexibility to proteins, allowing the signaling networks controlled by them to rapidly respond to the cell's environment. One of the major benefits of disordered proteins is that this property allows them to create multiple relationship with multiple binding partners without the limitation of single relationship with a single binding partner.