The potential of Electric Impedance Tomography (EIT) for localising seizure foci was examined in a rat model of epilepsy. The known seizure focus was successfully imaged, which appeared as a transient (~10 ms) decrease in impedance during spikes – due to the opening of ion channels, followed by a gradual increase in impedance as cells swelled.

International Steering Committee on Electrical Impedance Tomography
15th International Conference on Biomedical Applications of Electrical Impedance Tomography (EIT 2014)
International Steering Committee on Electrical Impedance Tomography

Vongerichten, Anna, Sato dos Santos, Gustavo, Aristovich, Kirill, McEvoy, Andrew, Walker, Matthew, & Holder, David. (2014). Imaging Epileptic Seizures in a Rat Model using Electric Impedance Tomography and its Clinical Implications. In 15th International Conference on Biomedical Applications of Electrical Impedance Tomography (EIT 2014). International Steering Committee on Electrical Impedance Tomography.