The highly selective oxidation chemistry carried out by fatty acid desaturases is a potentially important source of novel biocatalytic activity. Recent progress in the mechanistic understanding of this set of reactions will help to guide ongoing protein engineering experiments designed to modify desaturases for specific requirements.

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Journal Tetrahedron Asymmetry
Buist, P.H. (2004). Catalytic diversity of fatty acid desaturases. Tetrahedron Asymmetry (Vol. 15, pp. 2779–2785). doi:10.1016/j.tetasy.2004.07.053