A minor novel 1,7-naphthyridine alkaloid with an unprecedented skeleton, named anisopusine (1), was isolated from the CH 2Cl 2 soluble materials of an acetone extract of the bark of Anisopus mannii (Asclepiadaceae) together with four known compounds 5α-hydroxy-lup-20(29)- en-3β-yl eicosanoate (2), [6]-gingerdione (3), [6]-dehydrogingerdione (4), and ferulic acid (5). Their structures were determined on the basis of spectroscopic data, including 1D and 2D NMR, HREI-MS. Compounds (2-5) were characterized for the first time from this genus.

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Keywords 1,7-naphthyridine alkaloid, 5a-hydroxy-lup-20(29)-en-3β-yl eicosanoate, Anisopus mannii, Anisopusine, Asclepiadaceae, Gingerdione
Persistent URL dx.doi.org/10.1139/V08-170
Journal Canadian Journal of Chemistry
Tsopmo, A, Kamnaing, P. (Pierre), Watchueng, J. (Jean), Gao, J.-M. (Jin-Ming), Konishi, Y. (Yasuo), & Sterner, O. (Olov). (2009). Chemical constituents from the bark of Anisopus mannii. Canadian Journal of Chemistry, 87(2), 397–400. doi:10.1139/V08-170