Molecularly imprinted polymers for 90Sr urine bioassay
A molecularly imprinted polymer (MIP) comprising dicyclohexano-18-crown-6 (DCH18C6) was synthesized as a Sr-selective sorbent for urine bioassay purposes. MIP particles (326 ± 2 nm diameter) were formed using acetone and acetonitrile (1:3 v/v) as the porogen, methacrylic acid (MAA) as the functional monomer and ethylene glycol dimethacrylate (EGDMA) as the cross-linker. The DCH18C6-MIP particles were impregnated with additional DCH18C6 and treated further with NaOH to attain better binding affinity for Sr2+. The effects of pH, ionic strength and amount of particles were evaluated for optimal extraction of 90Sr2+ from urine samples, as measured by liquid scintillation analysis (LSA). After up to 94% of 90Y was removed by precipitation with TiO2, DCH18C6-MIP particles were applied for selective SPE of 90Sr remaining in the urine matrix for final LSA.
|Keywords||bioassay, emergency planning, excretion, urinary, liquid scintillation|
Bahraini, N. (Negar), Lai, E. P, Li, C. (Chunsheng), Sadi, B.B. (Baki B.), & Kramer, G.H. (Gary H.). (2011). Molecularly imprinted polymers for 90Sr urine bioassay. Health Physics, 101(2), 128–135. doi:10.1097/HP.0b013e318213a5ef