Hazardous compounds and bacteria in water have an adverse impact on human health and environmental ecology. Polydopamine (or polypyrrole)-coated magnetic nanoparticles and polymethacrylic acid-co-ethylene glycol dimethacrylate submicron particles were investigated for their fast binding kinetics with bisphenol A, proflavine, naphthalene acetic acid, and Escherichia coli. A new method was developed for the rapid determination of % binding by sequential injection of particles first and compounds (or E. coli) next into a fused-silica capillary for overlap binding during electrophoretic migration. Only nanolitre volumes of compounds and particles were sufficient to complete a rapid binding test. After heterogeneous binding, separation of the compounds from the particles was afforded by capillary electrophoresis. % binding was influenced by applied voltage but not current flow. In-capillary coating of particles affected the % binding of compounds.

Additional Metadata
Keywords Binding test, CE, Hazardous compounds, Polymer-modified magnetic nanoparticles, Polymethacrylic acid
Persistent URL dx.doi.org/10.1002/elps.201100106
Journal Electrophoresis
Iqbal, Z. (Zafar), Alsudir, S. (Samar), Miah, M. (Musharraf), & Lai, E. P. (2011). Rapid CE-UV binding tests of environmentally hazardous compounds with polymer-modified magnetic nanoparticles. Electrophoresis, 32(16), 2181–2187. doi:10.1002/elps.201100106