Molecularly imprinting technique was combined with magnetic nanoparticles to synthesize molecularly imprinted polymer-encapsulated particles for selective removal and efficient separation of estrogenic compounds from water. The core-shell-structured particles were successfully prepared by a novel 2-h ultrasonication-assisted synthesis in a mixture of water and organic solvent using dual-layer surfactant-modified magnetic particles as core, the most physiologically active estrogenic compound (17β-estradiol) as template, and widely adapted methacrylic acid as functional monomer. Ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, and magnetic separation were used to characterize the particles. High-performance liquid chromatography-tandem mass spectrometry was used for quantitative binding performance analysis at low-nanogram per milliliter levels. The particles exhibited satisfactory recognition of 17β-estradiol in water. They possessed great potential for rapid, cost-effective, and efficient separation of estrogenic compounds from aqueous environment with specificity. POLYM. ENG. SCI., 2012.

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Journal Polymer Engineering and Science
Xia, X. (Xinlong), Lai, E. P, & Örmeci, B. (2012). Ultrasonication-assisted synthesis of molecularly imprinted polymer-encapsulated magnetic nanoparticles for rapid and selective removal of 17β-estradiol from aqueous environment. Polymer Engineering and Science, 52(8), 1775–1783. doi:10.1002/pen.23126