Wood frogs survive extracellular freezing at moderate subzero temperatures (-4°C) for at least 11 days. Freezing survival is aided by the accumulation of high concentrations of glucose as a cryoprotectant in blood and tissues. Glucose production was accompanied by a rapid decline in liver, but not muscle, glycogen levels suggesting that liver is the organ controlling cryoprotectant synthesis.

cryoprotectant synthesis, frog, freeze tolerance, glucose levels, cryoprotectant, glycogen levels, liver, Rana sylvatica
Department of Biology

Storey, K. (1984). Freeze tolerance in the frog, Rana sylvatica. Experientia, 40(11), 1261–1262. doi:10.1007/BF01946664