Non-invasive monitoring of pulmonary artery pressure from timing information by EIT: Experimental evaluation during induced hypoxia
Monitoring of pulmonary artery pressure (PAP) in pulmonary hypertensive patients is currently limited to invasive solutions. We investigate a novel non-invasive approach for continuous monitoring of PAP, based on electrical impedance tomography (EIT), a safe, low-cost and non-invasive imaging technology. EIT recordings were performed in three healthy subjects undergoing hypoxia-induced PAP variations. The pulmonary pulse arrival time (PAT), a timing parameter physiologically linked to the PAP, was automatically calculated from the EIT signals. Values were compared to systolic PAP values from Doppler echocardiography, and yielded strong correlation scores (r = ?0.94±0.07) for all three subjects. Results suggest the feasibility of non-invasive, unsupervised monitoring of PAP.
|Keywords||continuous monitoring, EIT, electrical impedance tomography, non-invasive, PAP, pulmonary artery pressure, pulmonary hypertension|
Proença, M. (Martin), Braun, F. (Fabian), Solà, J. (Josep), Adler, A, Lemay, M. (Mathieu), Thiran, J.-P. (Jean-Philippe), & Rimoldi, S.F. (Stefano F.). (2016). Non-invasive monitoring of pulmonary artery pressure from timing information by EIT: Experimental evaluation during induced hypoxia. Physiological Measurement, 37(6), 713–726. doi:10.1088/0967-3334/37/6/713